Wednesday, July 16, 2014



Glutathione and the Role of Inflammation in MS.  Glutathione the key antioxidant in the brain.

In his book, Glutathione: Your Best Defense Against Aging, Cellular Damage and Disease, Dr. Keller discussed neurodegenerative diseases (Alzheimer’s, Parkinson’s, Multiple Sclerosis) and wrote:
It is impossible to argue that these are not devastating illnesses and a myriad of studies have associated them casually with inflammation. The question that remains is, if they are associated with increased free radical production (a given in states of inflammation) will ‘rebalancing the system with antioxidants prove clinically beneficial?’ ”
Dr. Keller’s question continues to be answered by scientific studies that propose that “antioxidants may inhibit the development and progression of MS lesions.” (Schreibelt, 2007— Follow this link to read the entire text of the published abstract on this study: www.ncbi.nlm.nih.gov/pubmed/17761296
A British study discussed the dangerous free radical nitric oxide and its derivative peroxynitrite and the role they play in inflammatory blood-brain-barrier dysfunction. (Giovannoni 1998— Follow this link to read the entire text of the published abstract on this study: www.ncbi.nlm.nih.gov/pubmed/9762676
In the March 2011 journal Multiple Sclerosis, researchers at the University of Kansas Medical Center concluded that in patients with secondary progressive multiple sclerosis that showed an absence of measurable inflammation, oxidative stress continued to cause a functional decline in the patients. This was shown by lower levels of glutathione in the brain. (Choi 2011— Follow this link to read the entire text of the published abstract on this study: www.ncbi.nlm.nih.gov/pubmed/20921235
The researchers confirmed that glutathione (GSH) is “a key antioxidant in the brain.”